Clinical research Paris Descartes Necker Cochin

First structure of institutional clinical research in France


Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

A multinational, randomized, double-blind, placebo-controlled trial of cannabidiol was conducted to treat drug-resistant epilepsy in the Dravet syndrome (a rare genetic form of epileptic encephalopathy

2016 activity

Ongoing studies : 592 including 241 perinatal and pediatric studies Publications : 128 publications in 2016 including 62 perinatal studies     

PHRC 2016 : results

The results of PHRC 2016 are now known. Our structure has been implied in 15 succesfull projects. They are listed below:

128 articles published in 2016

The URC/CIC Paris Descartes Necker Cochin has been implied in 128 publications in 2016. They are listed below:

Activity report

Notre bilan d'activité de recherche en 2017. Nous couvrons l'ensemble des spécialités médicales avec une spécificité concernant les études mère-enfant et les maladies rares.


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Trial management

Study design and protocol writing, data base programming, monitoring, data management, statistical analysis


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methodology/ modelling

Modeling : population pharmacokinetic, PB/PK study, Bayesian approach, sequential approach, big data


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Education and training

Planning of teachings, course materials about clinical research, and registration processses


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information consent readability

The Flesch index is an objective tool to evaluate the complexity of a text. Test the lisibility of the information letter dedicated to patients, or any other document


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Pharmacological dosages

We propose a large offer of drug dosages for research purpose (HPLC, LC MSMS). Please download the appropriate asking form.


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Research in clinical ethics

Clinical research in ethics related to research (information given to patients) and related to care (information given to adults and children, end-of-live in pediatrics)


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Regulatory texts

In this section, you will find regulatory texts for clinical research and ublishing guidelines for scientific articles and activity reports


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Tarnier

Tarnier

Hospital Tarnier 89, rue d'Assas 75006 Paris France

Imagine

Imagine

Imagine 24 Bvd du Montparnasse 75014 Paris Cedex 14 France

Maternity Port-Royal, Hospital Cochin

Maternity Port-Royal, Hospital Cochin

Maternity Port Royal, 123 Bd de Port Royal 75014 Paris Cedex 14 France

  • The clinical research associate (CRA) is a key link between the promoter and the investigators. He is responsible for the initiation and follow-up of clinical studies, but also for the quality and authenticity of clinical data.

    Clinical Research Associate

    Clinical Research Associate

  • The clinical research technician participates in clinical data collection and in-site inclusions in collaboration with investigators and medical team of hospital. He also ensures that the clinical study is made in respect of SOPs and GCP, and that the quality control is optimal.

    Clinical Research Technician

    Clinical Research Technician

  • The project manager coordinates the implementation and development of clinical research projects, in accordance with regulatory requirements

    Project Manager

    Project Manager

  • The data manager is on the border between informatics and medicine. From crf design to final database extraction, he allows the relevance and quality of all the data related to a clinical trial.

    Data Manager

    Data manager

  • The QA manager ensures that all activities are performed in accordance with GMP, company SOPs, and Health and Safety policies. He coordinates the QA management system, manages a self-inspection program to prepare to external audits, and ensures an internal formation program to maintain an up to date knowledge of all employees

    QA Coordination

    QA

  • The role of statistician is to applied statistical methods to medical and scientific research. He participates to data interpretation and is essential to publication of scientific research

    Biostatisticien

    BIO